How to use

Treating with Lasix ONYU

For Healthcare Professionals

A New Pathway for Heart Failure Management

Lasix ONYU offers an alternative, cost-effective treatment option for managing edema caused by fluid build-up in adult patients with chronic heart failure. By enabling at-home treatment, Lasix ONYU may support efforts to optimize healthcare resource utilization, while enhancing patient access and convenience.

Successful implementation requires collaboration across hospitals, provider networks, and care teams. We are committed to partnering with healthcare organizations to assist in integrating Lasix ONYU into existing care pathways.

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Collaboration to Transition Care Home

Lasix ONYU changes traditional care pathways, however successful implementation requires coordination across providers and payors. Our approach begins with provider interest, followed by collaboration to align with payor policies and reduce access barriers like prior authorizations or high co-pays.

Distribution and Access

Lasix ONYU is available through leading pharmaceutical distributors, including 340B contract pharmacies. It is available in emergency departments, clinics, and other care settings. Training is simple and can be initiated with the first unit. Patients can leave with the device placed and begin treatment at home.

Supporting Clinical Workflows

Lasix ONYU is designed to integrate into a variety of clinical workflows that aim to support outpatient management of fluid overload in adult patients with chronic heart failure.

It may be used to initiate treatment in the emergency department or observation unit, allowing certain patients to be safely discharged home and potentially avoid inpatient admission. In outpatient clinics, it offers an option for earlier intervention in lower-acuity patients under the care of healthcare professionals. Lasix ONYU can also support transitions such as completing decongestion at home after an inpatient stay or addressing worsening symptoms during post-discharge follow-up. For patients with frequent hospitalizations, it may enable more proactive, scheduled management in the outpatient setting. In hospital-at-home programs, Lasix ONYU may serve as an alternative when IV access or continuous monitoring is not required. It may also play a role in hospice and palliative care by supporting symptom relief outside of the hospital environment.

Interested in implementing Lasix ONYU in your practice?

If you’re a healthcare provider ready to explore how Lasix ONYU can support at-home decongestion for your patients, contact us below.

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What is Lasix® ONYU (furosemide injection) for subcutaneous use?

Lasix ONYU is a prescription drug-device combination that treats edema caused by fluid build-up in a person with heart failure. Lasix ONYU comes with a special device that delivers the medicine under the skin. Follow the instructions provided by your healthcare provider when using Lasix ONYU.

IMPORTANT SAFETY INFORMATION

Before using Lasix ONYU, read the Instructions for Use and tell your healthcare provider about all your medical conditions, including if you are allergic to furosemide or any of the ingredients in Lasix ONYU, have trouble urinating, or if you are allergic to medical adhesives.

Tell your healthcare provider about all of the medicines you take, including prescription and over-the-counter medicines.

Warning: Only use the Lasix ONYU Prefilled Cartridge with the Lasix ONYU Infusor. Do not use insulin cartridges or other medicine cartridges in the Lasix ONYU Infusor. Doing so could cause severe injury.

What are the possible side effects of Lasix ONYU?

Dehydration: Lasix ONYU is a diuretic that can make you lose a lot of fluid and with it electrolytes. You may get a dry mouth, have increased thirst, get muscle pains or cramps, have reduced urine output or your urine may be more yellow than normal, you may get a headache, get dry skin, or have nausea or vomiting. Your healthcare provider may check your electrolytes while receiving Lasix ONYU.

Low Blood Pressure: Lasix ONYU may lower your blood pressure temporarily. You may feel lightheaded or dizzy. This usually happens when you stand. Getting up slowly may help.

High Blood Sugar: Lasix ONYU may increase blood sugar (glucose) levels if you have diabetes mellitus.

Loss of Hearing: Lasix ONYU can cause ringing in your ears. If so tell your healthcare provider.

Risk of Sunburn: Your skin may be more sensitive to sunlight while taking Lasix ONYU.

Infusion Site Reactions: Lasix ONYU can cause infusion site pain, bruising, and temporary swelling or redness at the site of the Infusor.

Incomplete Dosing: Make sure the Infusor does not get wet during use. Also limit your physical activities.  Some movements or when it gets wet may stop the infusion and you may not get all the medication.

These are not all the possible side effects of Lasix ONYU. For more information, ask your healthcare provider or pharmacist.

Call your healthcare provider for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Please see Lasix® ONYU full Prescribing Information and Instructions for Use.

INDICATION & LIMITATION OF USE

Lasix® ONYU is a prescription drug-device combination that treats edema in adult patients with chronic heart failure.  It enables treatment outside the healthcare setting as instructed by a healthcare provider.

INDICATION AND USAGE

Lasix ONYU is indicated for the treatment of edema in adult patients with chronic heart failure.

Contraindications

  • Lasix ONYU is contraindicated in patients with anuria.
  • Lasix ONYU is contraindicated in patients with a history of hypersensitivity to furosemide or medical adhesives.
  • Lasix ONYU is contraindicated in patients with hepatic cirrhosis.

 

Warnings and Precautions

  • Fluid, Electrolyte, and Metabolic Abnormalities: Monitor serum electrolytes, CO2, BUN, creatinine, glucose, and uric acid.
  • Worsening Renal Function: Monitor for dehydration and azotemia.
  • Ototoxicity: Avoid higher than recommended doses.
  • Acute Urinary Retention: Monitor patients with symptoms of urinary retention.
  • Incomplete Dosing: Fluid contact and certain patient movements during treatment may cause the On-body Infusor to prematurely terminate infusion. Ensure patients can detect and respond to alarms.

Adverse Reactions

The most common adverse reactions during treatment with the Lasix ONYU Infusor were administration site and skin reactions: erythema, bruising, edema, and infusion site pain.

Drug Interactions

  • Aminoglycoside antibiotics: Increased potential ototoxicity of the antibiotics. Avoid combination.
  • Ethacrynic acid: Risk of ototoxicity. Avoid combination.
  • Salicylates: Risk of salicylate toxicity.
  • Cisplatin and nephrotoxic drugs: Risk of ototoxicity and nephrotoxicity.
  • Lithium: Risk of lithium toxicity.
  • Renin-angiotensin inhibitors: Increased risk of hypotension and renal failure.
  • Adrenergic blocking drugs: Risk of potentiation.
  • Drugs undergoing renal tubular secretion: Risk of toxicity potentiation.

Please see Lasix® ONYU full Prescribing Information and Instructions for Use.