How to use

Ordering Information

Lasix ONYU is now available to order through Cardinal Health Specialty Pharmaceutical Distribution (SPD) and Cencora Specialty Distribution (formerly AmerisourceBergen).

Please note: To administer Lasix ONYU, a Reusable Unit (RU) is required (UPC: 381137901317). The Reusable Unit is for single-patient use and may be used for up to 48 treatments.

Distributor Information

Cardinal Health Specialty
Pharmaceutical Distribution (SPD)

Phone: 1-800-926-3161

Websites:
•Order Express
•Vantus HQ

Ordering Options:
Customers may place orders through Cardinal SPD using any of the following methods:

  1. Log in to Order Express
  2. Use Vantus HQ
  3. Call Pharmaceutical Customer Service at
    1-800-926-3161
Cencora Specialty Distribution
(formerly AmerisourceBergen)

Phone: 1-800-746-6273

Website: ABC Order
Fax: 1-800-547-9413
Email: service@asdhealthcare.com

Ordering Options:
Customers may place orders through Cencora using either of the following methods:

  1. Log in to ABC Order under their own profile
  2. Contact Customer Service via phone, fax, or email:
CASE SIZE: Both the Lasix ONYU kit and the Reusable Unit and Charger box come in a case of 24 units.

 For questions related to ordering, please contact distribution@sqinnovation.com

Product Information

 Product Package Contents
NDC:
81137-001-15		Lasix ONYU KitCarton containing one 80 mg/2.67 mL single- dose prefilled cartridge co-packaged with one Disposable Unit (DU) and two alcohol pads
UPC: 81137901317

Lasix ONYU Reusable Unit and Charger Box

Carton containing one Reusable Unit (RU), charger, and Instructions for Use

Please read the Important Safety Information, full Prescribing Information and Instructions for Use. 

What is Lasix® ONYU (furosemide injection) for subcutaneous use?

Lasix ONYU is a prescription drug-device combination that treats edema caused by fluid build-up in a person with heart failure. Lasix ONYU comes with a special device that delivers the medicine under the skin. Follow the instructions provided by your healthcare provider when using Lasix ONYU.

IMPORTANT SAFETY INFORMATION

Before using Lasix ONYU, read the Instructions for Use and tell your healthcare provider about all your medical conditions, including if you are allergic to furosemide or any of the ingredients in Lasix ONYU, have trouble urinating, or if you are allergic to medical adhesives.

Tell your healthcare provider about all of the medicines you take, including prescription and over-the-counter medicines.

Warning: Only use the Lasix ONYU Prefilled Cartridge with the Lasix ONYU Infusor. Do not use insulin cartridges or other medicine cartridges in the Lasix ONYU Infusor. Doing so could cause severe injury.

What are the possible side effects of Lasix ONYU?

Dehydration: Lasix ONYU is a diuretic that can make you lose a lot of fluid and with it electrolytes. You may get a dry mouth, have increased thirst, get muscle pains or cramps, have reduced urine output or your urine may be more yellow than normal, you may get a headache, get dry skin, or have nausea or vomiting. Your healthcare provider may check your electrolytes while receiving Lasix ONYU.

Low Blood Pressure: Lasix ONYU may lower your blood pressure temporarily. You may feel lightheaded or dizzy. This usually happens when you stand. Getting up slowly may help.

High Blood Sugar: Lasix ONYU may increase blood sugar (glucose) levels if you have diabetes mellitus.

Loss of Hearing: Lasix ONYU can cause ringing in your ears. If so tell your healthcare provider.

Risk of Sunburn: Your skin may be more sensitive to sunlight while taking Lasix ONYU.

Infusion Site Reactions: Lasix ONYU can cause infusion site pain, bruising, and temporary swelling or redness at the site of the Infusor.

Incomplete Dosing: Make sure the Infusor does not get wet during use. Also limit your physical activities.  Some movements or when it gets wet may stop the infusion and you may not get all the medication.

These are not all the possible side effects of Lasix ONYU. For more information, ask your healthcare provider or pharmacist.

Call your healthcare provider for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Please see Lasix® ONYU full Prescribing Information and Instructions for Use.

INDICATION & LIMITATION OF USE

Lasix® ONYU is a prescription drug-device combination that treats edema in adult patients with chronic heart failure.  It enables treatment outside the healthcare setting as instructed by a healthcare provider.

INDICATION AND USAGE

Lasix ONYU is indicated for the treatment of edema in adult patients with chronic heart failure.

Contraindications

  • Lasix ONYU is contraindicated in patients with anuria.
  • Lasix ONYU is contraindicated in patients with a history of hypersensitivity to furosemide or medical adhesives.
  • Lasix ONYU is contraindicated in patients with hepatic cirrhosis.

 

Warnings and Precautions

  • Fluid, Electrolyte, and Metabolic Abnormalities: Monitor serum electrolytes, CO2, BUN, creatinine, glucose, and uric acid.
  • Worsening Renal Function: Monitor for dehydration and azotemia.
  • Ototoxicity: Avoid higher than recommended doses.
  • Acute Urinary Retention: Monitor patients with symptoms of urinary retention.
  • Incomplete Dosing: Fluid contact and certain patient movements during treatment may cause the On-body Infusor to prematurely terminate infusion. Ensure patients can detect and respond to alarms.

Adverse Reactions

The most common adverse reactions during treatment with the Lasix ONYU Infusor were administration site and skin reactions: erythema, bruising, edema, and infusion site pain.

Drug Interactions

  • Aminoglycoside antibiotics: Increased potential ototoxicity of the antibiotics. Avoid combination.
  • Ethacrynic acid: Risk of ototoxicity. Avoid combination.
  • Salicylates: Risk of salicylate toxicity.
  • Cisplatin and nephrotoxic drugs: Risk of ototoxicity and nephrotoxicity.
  • Lithium: Risk of lithium toxicity.
  • Renin-angiotensin inhibitors: Increased risk of hypotension and renal failure.
  • Adrenergic blocking drugs: Risk of potentiation.
  • Drugs undergoing renal tubular secretion: Risk of toxicity potentiation.

Please see Lasix® ONYU full Prescribing Information and Instructions for Use.